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Université de Fribourg

A randomized comparison of platelet reactivity in patients after treatment with various commercial clopidogrel preparations: The CLO-CLO trial = Étude randomisée comparant la réactivité plaquettaire des patients traités par diverses préparations commerciales de clopidogrel. Étude CLO-CLO

Oberhänsli, Markus ; Lehner, Cédric ; Puricel, Serban ; Lehmann, Sonja ; Togni, Mario ; Stauffer, Jean-Christophe ; Baeriswyl, Gérard ; Goy, Jean-Jacques ; Cook, Stéphane

In: Archives of Cardiovascular Diseases, 2012, vol. 105, no. 11, p. 587–592

BackgroundThe salt linked to the clopidogrel molecule in generic preparations is suspected to affect its clinical efficacy. There is a lack of information about inhibition of platelet reactivity by generic preparations.AimsTo compare the effect of original clopidogrel (clopidogrel bisulphate [Plavix®]), generic clopidogrel preparations (clopidogrel hydrochloride...

Université de Fribourg

Balloon angioplasty using the "grip" scoring balloon for treatment of coronary in-stent restenosis - immediate and 12-month clinical outcomes

Puricel, Serban ; Schoepke, Linus ; Togni, Mario ; Oberhänsli, Markus ; Moschovitis, Aris ; Meier, Bernhard ; Windecker, Stephan ; Cook, Stéphane

In: Cardiovascular Medicine, 2012, vol. 15, no. 12, p. 354–361

Objectives: We sought to determine the efficacy and safety of a scoring balloon for the treatment of in-stent restenosis (ISR). Background: The optimal therapy for ISR is not yet properly established and subject to many discussions. The GRIP™ Balloon (Acrostak, Switzerland) might be of interest for the treatment of certain types of ISR. Methods: Between 2003 and 2009, 157 patients who were...

2 results 1